New Insight Into How Ketamine Works in Depression
Ketamine exerts an initial antidepressant effect by blocking the N-methyl-D-aspartate receptor (NMDAR), and the ketamine metabolite hydroxynorketamine (HNK) may extend the duration of the effect. The findings could lead to the development of safer alternatives. more… (registration required)
Inside the Los Angeles Clinic That Uses Ketamine to Treat Depression
Depression is all too common, especially among people in the tech sector. That’s why denizens of Silicon Beach have been flocking to a local clinic that offers a radical alternative when standard treatments fall short. more…
FDA Data Support Ketamine as Depression Therapy
An analysis of data from the FDA Adverse Events Reporting System (FAERS) supported previous findings that ketamine could be an effective treatment for depression, researchers found. more…
Ketamine For Severe Depression: ‘How Do You Not Offer This Drug To People?’
Gerard Sanacora, a professor of psychiatry at Yale University, has treated hundreds of severely depressed patients with low doses of ketamine, an anesthetic and popular club drug that isn’t approved for depression. more…
A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders
Several studies now provide evidence of ketamine hydrochloride’s ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant to treatment. Despite the relatively small sample sizes, lack of longer-term data on efficacy, and limited data on safety provided by these studies, they have led to increased...
