Coronavirus Anxiety Syndrome

Many of our ketamine therapy patients tell us that the COVID-19 pandemic is causing a dramatic increase in their anxiety. This is understandable, but there are steps you can take to minimize the impact of the pandemic on your mental health.

  1. Physical distancing and social connection: While the experts’ advice to stay home and minimize physical contact are well-founded, it is also well known that anxiety and depression disorders thrive in patients who isolate. Therefore, until the crisis settles down, balance physical distancing with social connection. Call that old friend you have not talked to in a while. Skype, Zoom, text, email, and social media can all be used for support. You will be rewarded, and you will help each person you connect with as well.
  • Practice self-care: Now more than ever, maintain the rituals that help you achieve balance and serenity. Exercise, eat healthy foods, meditate, journal, take a long hot bath, do whatever nurtures and sustains you.
  • Stay proactive with your mental health: Maintain your weekly visits with your therapist, perhaps by video chat. Continue taking your psychiatric medications, including your ketamine therapy. Stay on top of it and keep a preventive mindset. Many of our patients have told us that ketamine boosts their resilience to life’s stresses; this is a time when all of us need as much resilience as possible. If you allow yourself to fall behind, it will be that much more difficult to pull out of your emotional crash back into homeostasis. This is especially true with unusually intense external stressors, such as coronavirus anxiety syndrome.
  • Limit exposure to the news: Remember that the news media uses fear and sensationalism to increase their profit margins. Stay up to date, but do so in moderation, or your quest for the latest information will make you feel more anxious, rather than empowered. Additionally, try to limit your information sources to reliable authorities, such as the CDC and the WHO.  
  • Follow the CDC’s guidelines, but do not overdo them: Avoid crowds, wash your hands frequently, and disinfect frequently touched surfaces. These lower your risk of contracting and spreading the virus. However, especially for patients with OCD and anxiety disorders, compulsive (rather than appropriate) handwashing will actually make you more anxious. Balance and moderation are key.

FDA Approval Expected Monday of Ketamine-derived “Spravato”





  • SpravatoTM, a form of ketamine, will be FDA approved on Monday for Treatment Resistant Depression and for Major Depression with suicidality.

  • FDA approval will result in insurance coverage for this form of ketamine, for this purpose, which will make it affordable for millions of suffering patients.

  • Although it is not as effective as an anti-depressant as the original formulation of ketamine, SpravatoTM should still help many people who have not had success with traditional anti-depressants, such as SSRIs.

  • SpravatoTM will only be given in a medical clinic, by healthcare providers. It will not be for at-home use.

  • Patients will receive SpravatoTM as a nasal spray. They will be required to stay for two hours in the medical clinic afterwards, so they can be monitored for elevated blood pressure, sedation, visual disturbances, and other potential side-effects. They will not be permitted to drive for the rest of the day.

  • SpravatoTM will be given twice a week for 4 weeks initially, then once weekly or every other week.


Ketamine was originally approved by the FDA as an anesthetic in 1970. The ketamine molecule comes in two mirror-image forms: a left-handed version, aka S-ketamine (the S is for sinistra, which is latin for left) and R-ketamine, the right-handed form. When the FDA approved ketamine in 1970, it was for racemic ketamine, which is simply a 50:50 mixture of the left and right-handed variations of the molecule. At Boulder Mind Care, we have been administering racemic ketamine to our patients since we opened our doors.


Interestingly, the two different forms of ketamine, when isolated and compared to each other, have quite different characteristics. R-ketamine is a more potent anti-depressant. S-ketamine is better at alleviating certain types of chronic pain.

Racemic ketamine became generic several decades ago. However, when ketamine’s paradigm-busting effectiveness in depression and anxiety disorders became apparent, Big Pharma giant Johnson & Johnson’s subsidiary Janssen Pharmaceuticals decided to cash in. Their strategy: applying for FDA approval of the S-ketamine molecule for Treatment Resistant Depression. Even though drug companies cannot profit from generic ketamine, Janssen exploited a loophole in the New Drug Application patent laws in the United States, by using only the left-handed version of ketamine. Janssen is projected to bring in annual revenue from $490 million to as much as a billion dollars from SpravatoTM.

In 2016 the FDA fast-tracked the approval process for Spravato, recognizing the unmet need of millions still suffering from treatment resistant depression, and that FDA approval will also mean coverage by insurance companies. However, only two of J&J’s five pivotal clinical trials in support of the marketing application were considered successful. Despite this, on February 13th the FDA advisory committee voted 14-2 in favor of Spravato coming to market. The FDA’s willingness to accept a lower standard of efficacy evidence stems from the dire need for insurance coverage and additional treatment options for treatment-resistant depression, which is associated with a higher risk of self-harm and suicide.

Racemic ketamine has been studied much more extensively over the past 19 years, and has been demonstrated to be a superior anti-depressant than esketamine. In addition, intravenous infusion is the route of administration in the vast majority of the research studies to date, and remains the gold standard for precision dosing. Nonetheless, we are excited by the arrival of Spravato. J&J’s marketing campaign will raise public awareness of both types of ketamine in the treatment of mood disorders. Suicide is the tenth largest cause of death in the US, and the only one that is increasing every year. We need all the help we can get!


, ,

End The Stigma!

Lady Gaga and Bradley Cooper did a masterful remake of “A Star is Born”, now in theaters. We highly recommend it! The issues of mental health and drug addiction are more timely than ever. Also, see Lady Gaga’s op-ed at lady-gaga-op-ed-on-suicide-and-mental-health.


New Psychology Today article on Ketamine

The current edition of Psychology Today has a (mostly accurate) article about the revolutionary success ketamine has in treating depression and PTSD. We applaud their raising public awareness about the fact that ketamine removes suicidality within hours, and that it works overall in about 70 percent of patients who have not gotten adequate relief from conventional anti-depressants. Ketamine is a game-changer.

Read the article

Don’t wait any longer, contact us now and begin to “Love Your Life”!

Click HERE to get started, and go to the New Patient area

, ,

Dr. Sanjay Gupta on CNN: “Ketamine offers lifeline for people with severe depression, suicidal thoughts”

In this post, a Wisconsin man who had been on the brink of suicide, told CNN’s Sanjay Gupta how Ketamine infusions stopped his suicidal thinking after traditional anti-depressants failed him. At our Boulder Ketamine Infusion Clinic, we see such dramatic, life-changing responses in our patients every week.

If you or a loved one are suffering with depression, suicidal thinking, PTSD, or severe anxiety, contact us now at Boulder Mind Care to turn your life around and “Love Your Life!”.

, ,

The Resurgence of Psychedelics in Medicine

There has been a flurry of articles in the media recently touting the successful use of psychedelics in medicine. Tim Ferriss, the New-York Times bestselling author, blogger, and angel investor, whose podcast has over 200 million downloads, recently interviewed Michael Pollan about his new book on the emerging science of psychedelics in what Ferriss dubbed “the most important podcast episode  I’ve put out in the last two years”.

Ferriss is so passionate about this topic that he has publicly committed to donating a million dollars of his own money to support the scientific study of psychedelic compounds.

Examples of the emerging successful use of these compounds in medicine include ketamine for depression, PTSD, anxiety, and chronic pain, MDMA for psychotherapy and PTSD, psilocybin for cluster headaches and terminal cancer patients, and Ibogaine for drug addiction.

Here in the front range of Northern Colorado, local journalist Reilly Capps recently published an interesting article on the topic as well.

Indeed, ketamine infusions are not voodoo medicine, not fringe science, rather they truly are a paradigm-shifting revolution.