
How Untreated Depression Contributes to the Opioid Epidemic
It can sometimes seem strange how so much of the country got hooked on opioids within just a few years. Deaths from prescription drugs like oxycodone, hydrocodone, and methadone have more than quadrupled since 1999, according to the CDC. But pain doesn’t seem to be the only culprit: About one-third of Americans have chronic pain, but not all of...

FDA Data Support Ketamine as Depression Therapy
An analysis of data from the FDA Adverse Events Reporting System (FAERS) supported previous findings that ketamine could be an effective treatment for depression, researchers found. more…

Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications
Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of eight million reports from the FDA Adverse Effect Reporting System. The results of the examination of population scale data...

Use and Safety of Ketamine: In Plain Terms
Not surprisingly, a number of you have voiced your concern about our intention to conduct a study in which ketamine, a drug known to be abused recreationally and commonly used by veterinarians, will be trialed in children. However, the current use, safety and benefits of ketamine are much greater than you might suspect. more…

Depression: How effective are antidepressants?
Like psychological approaches, antidepressants are a key part of treating depression. They aim to relieve symptoms and prevent depression from coming back. more…