Ketamine Infusions Provide Effective Relief for Severe Chronic Headache
Medical research is revealing more and more applications for ketamine, the old drug being used in new ways. Just as with Treatment Resistant Depression, where ketamine provides relief in 80% of patients, it is also often successful at relieving intractable headache pain. Indeed, the term “Treatment-Resistant Headache” could be used for the millions of women...

New Insight Into How Ketamine Works in Depression
Ketamine exerts an initial antidepressant effect by blocking the N-methyl-D-aspartate receptor (NMDAR), and the ketamine metabolite hydroxynorketamine (HNK) may extend the duration of the effect. The findings could lead to the development of safer alternatives. more… (registration required)

FDA Data Support Ketamine as Depression Therapy
An analysis of data from the FDA Adverse Events Reporting System (FAERS) supported previous findings that ketamine could be an effective treatment for depression, researchers found. more…

Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications
Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of eight million reports from the FDA Adverse Effect Reporting System. The results of the examination of population scale data...

Analysis of print news media framing of ketamine treatment in the United States and Canada from 2000 to 2015
There are multifaceted views on the use of ketamine, a potentially addictive substance, to treat mental health problems. The past 15 years have seen growing media coverage of ketamine for medical and other purposes. This study examined the print news media coverage of medical and other uses of ketamine in North America to determine orientations...