Ketamine – The Most Powerful Treatment For Depression Yet Invented
Ketamine continues to gain recognition, by both lay public and medical professionals, as a remarkably effective antidepressant, with minimal side effects and a much faster onset time compared to traditional antidepressants. These differences are explained by Ketamine’s mechanisms of action, which are multiple. The most important is by correcting the glutaminergic dysregulation seen in major...

How Untreated Depression Contributes to the Opioid Epidemic
It can sometimes seem strange how so much of the country got hooked on opioids within just a few years. Deaths from prescription drugs like oxycodone, hydrocodone, and methadone have more than quadrupled since 1999, according to the CDC. But pain doesn’t seem to be the only culprit: About one-third of Americans have chronic pain, but not all of...

Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications
Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of eight million reports from the FDA Adverse Effect Reporting System. The results of the examination of population scale data...

Use and Safety of Ketamine: In Plain Terms
Not surprisingly, a number of you have voiced your concern about our intention to conduct a study in which ketamine, a drug known to be abused recreationally and commonly used by veterinarians, will be trialed in children. However, the current use, safety and benefits of ketamine are much greater than you might suspect. more…

Ketamine for Treatment-Resistant Depression: Top 10 Medical Innovations 2017
In this video, see why Ketamine for Treatment-Resistant Depression was one the Cleveland Clinic’s Top 10 Medical Innovations for 2017.